The Comparation of Intraperitoneal Injection and Nasal-only Delivery Allergic Rhinitis Model Challenged With Different Allergen Concentration

2019149 citationsJournal Article

Authors

Ying Wang · Huazhong University of Science and Technology

Yue Zhou · Huazhong University of Science and Technology

Yun Zhu · Union Hospital

Wenting Yu · Union Hospital

Jinghui Wang

Junmei Fu · The First People's Hospital of Jiangxia District

Yang Yuan · Chinese People's Liberation Army

Abstract

The IP injection model and the nasal-only delivery model are 2 typical models for AR that causes a different immune response. A positive dose-response relationship in the nasal-only delivery model is observed from 25 mg/mL to 0.025 mg/mL.

Topics & Keywords

Allergic Rhinitis and Sensitization Asthma and respiratory diseases Dermatology and Skin Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: American Journal of Rhinology and Allergy

Volume 33, Issue 2, pp. 145-152

DOI: 10.1177/1945892418817221

Field-Weighted Citation Impact: 10.17