Prevention of HIV-1 Transmission Through Breastfeeding: Efficacy and Safety of Maternal Antiretroviral Therapy Versus Infant Nevirapine Prophylaxis for Duration of Breastfeeding in HIV-1-Infected Women With High CD4 Cell Count (IMPAACT PROMISE): A Randomized, Open-Label, Clinical Trial

2017208 citationsJournal Articlegreen Open Access

Authors

Patricia M. Flynn · St. Jude Children's Research Hospital

Taha E. Taha · Johns Hopkins University

Mae Cababasay · Cancer Research And Biostatistics

Mary Glenn Fowler · Johns Hopkins Medicine

Lynne Mofenson · Elizabeth Glaser Pediatric AIDS Foundation

Maxensia Owor · MUJHU Research Collaboration

Susan A. Fiscus

Abstract

Both mART and iNVP prophylaxis strategies were safe and associated with very low breastfeeding HIV-1 transmission and high infant HIV-1-free survival at 24 months.

Topics & Keywords

HIV/AIDS Research and Interventions HIV Research and Treatment HIV-related health complications and treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAIDS Journal of Acquired Immune Deficiency Syndromes

Volume 77, Issue 4, pp. 383-392

DOI: 10.1097/qai.0000000000001612

Field-Weighted Citation Impact: 7.44