Surgical Performance Determines Functional Outcome Benefit in the Minimally Invasive Surgery Plus Recombinant Tissue Plasminogen Activator for Intracerebral Hemorrhage Evacuation (MISTIE) Procedure

2019142 citationsJournal Articlebronze Open Access

Authors

Issam A. Awad · Johns Hopkins University

Sean P. Polster · Johns Hopkins University

Julián Carrión‐Penagos · Johns Hopkins University

Richard E. Thompson · Johns Hopkins University

Ying Cao · Johns Hopkins University

Agnieszka Stadnik · Johns Hopkins University

Patricia Lynn Money

Abstract

This is the first surgical trial reporting thresholds for reduction of ICH volume correlating with improved mortality and functional outcomes. To realize the benefit of surgery, protocol objectives, surgeon education, technical enhancements, and case selection should be focused on this goal.

Topics & Keywords

Intracerebral and Subarachnoid Hemorrhage Research Acute Ischemic Stroke Management Neurosurgical Procedures and Complications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neurosurgery

Volume 84, Issue 6, pp. 1157-1168

DOI: 10.1093/neuros/nyz077

Field-Weighted Citation Impact: 11.12