Human bone marrow mesenchymal stem cells-derived exosomes alleviate liver fibrosis through the Wnt/β-catenin pathway

2019314 citationsJournal Articlegold Open Access

Authors

Xiaoli Rong · Union Hospital

Junzhi Liu · Union Hospital

Xia Yao · Changchun University

Tiechao Jiang · Jilin University

Yimin Wang · Jilin University

Feng Xie · Jilin University

Abstract

These results suggest that hBM-MSCs-Ex treatment could ameliorate CCl<sub>4</sub>-induced liver fibrosis via inhibition of HSC activation through the Wnt/β-catenin pathway.

Topics & Keywords

Liver physiology and pathology Liver Disease Diagnosis and Treatment Organ Transplantation Techniques and Outcomes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Stem Cell Research & Therapy

Volume 10, Issue 1, pp. 98-98

DOI: 10.1186/s13287-019-1204-2

Field-Weighted Citation Impact: 21.39