Evaluation of Prospective<i>HLA-B*13:01</i>Screening to Prevent Dapsone Hypersensitivity Syndrome in Patients With Leprosy

201974 citationsJournal Articlebronze Open Access

Authors

Hong Liu · Shandong University

Zhenzhen Wang · Shandong Provincial Institute of Dermatology and Venereology

Fangfang Bao · Shandong Provincial Institute of Dermatology and Venereology

Chuan Wang · Shandong Provincial Institute of Dermatology and Venereology

Lele Sun · Shandong Provincial Institute of Dermatology and Venereology

Huimin Zhang · Shandong Provincial Institute of Dermatology and Venereology

Abstract

Prospective HLA-B*13:01 screening and subsequent elimination of dapsone from MDT for patients with HLA-B*13:01-positive leprosy may significantly reduce the incidence of DHS in the Chinese population.

Topics & Keywords

Drug-Induced Adverse Reactions Autoimmune Bullous Skin Diseases Immunodeficiency and Autoimmune Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA Dermatology

Volume 155, Issue 6, pp. 666-666

DOI: 10.1001/jamadermatol.2018.5360

Field-Weighted Citation Impact: 7.88