RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3

2019618 citationsJournal Articlegold Open Access

Authors

Yi Niu · Sun Yat-sen University

Ziyou Lin · Sun Yat-sen University

Arabella Wan · Sun Yat-sen University

Honglei Chen · Sun Yat-sen University

Heng Liang · Sun Yat-sen University

Lei Sun · Sun Yat-sen University

Yuan Wang · Guangzhou Medical University

Abstract

Our findings demonstrate the functional significance of the m6A modification in breast cancer, and suggest that FTO may serve as a novel potential therapeutic target for breast cancer.

Topics & Keywords

RNA modifications and cancer Cancer-related molecular mechanisms research Circular RNAs in diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Molecular Cancer

Volume 18, Issue 1, pp. 46-46

DOI: 10.1186/s12943-019-1004-4

Field-Weighted Citation Impact: 32.75