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Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens

20191,394 citationsJournal Articlegreen Open Access

Authors

Fiona M. Behan · Open Targets

Francesco Iorio · Wellcome Sanger Institute

Gabriele Picco · Wellcome Sanger Institute

Emanuel Gonçalves · Wellcome Sanger Institute

Charlotte Beaver · Wellcome Sanger Institute

Giorgia Migliardi · Candiolo Cancer Institute

Topics & Keywords

CRISPR and Genetic Engineering DNA Repair Mechanisms Genomics and Chromatin Dynamics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Nature

Volume 568, Issue 7753, pp. 511-516

DOI: 10.1038/s41586-019-1103-9

Field-Weighted Citation Impact: 66.35

Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens | Researchclopedia

GlaxoSmithKline (United Kingdom)

Yanhua Rao · GlaxoSmithKline (United States)

Francesco Sassi · Candiolo Cancer Institute

Marika Pinnelli · Candiolo Cancer Institute

Rizwan Ansari · Wellcome Sanger Institute

Sarah Harper · Wellcome Sanger Institute

David A. Jackson · Wellcome Sanger Institute

Rebecca McRae · Wellcome Sanger Institute

Rachel Pooley · Wellcome Sanger Institute

Piers Wilkinson · Wellcome Sanger Institute

Dieudonne van der Meer · Wellcome Sanger Institute

David J. Dow · GlaxoSmithKline (United Kingdom)

Carolyn Buser‐Doepner · Open Targets

Andrea Bertotti · Candiolo Cancer Institute

Livio Trusolino · Candiolo Cancer Institute

Euan A. Stronach · Open Targets

Julio Sáez-Rodríguez · RWTH Aachen University

Kosuke Yusa · Open Targets

Mathew J. Garnett · Wellcome Sanger Institute