APOL1 Risk Genotypes Are Associated With Early Kidney Damage in Children in Sub-Saharan Africa

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Authors

Pépé Mfutu Ekulu · University of Kinshasa

Agathe B. Nkoy · University of Kinshasa

D. Betukumesu · University of Kinshasa

Michel Ntetani Aloni · University of Kinshasa

Jean Robert Makulo · University of Kinshasa

Ernest Kiswaya Sumaili · University of Kinshasa

Éric Mafuta ·

Abstract

The <i>APOL1</i> risk variants are prevalent in children living in DRC. HRG carriers have increased odds of early kidney disease, and infection with HIV dramatically increases this probability.

Topics & Keywords

Renal Diseases and Glomerulopathies Chronic Lymphocytic Leukemia Research Chronic Kidney Disease and Diabetes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Kidney International Reports

Volume 4, Issue 7, pp. 930-938

DOI: 10.1016/j.ekir.2019.04.002

Field-Weighted Citation Impact: 5.54