Genetic Testing and Results in a Population-Based Cohort of Breast Cancer Patients and Ovarian Cancer Patients

2019373 citationsJournal Articlegreen Open Access

Authors

Allison W. Kurian · Stanford University

Kevin C. Ward · Emory University

Nadia Howlader · National Cancer Institute

Dennis Deapen · University of Southern California

Ann S. Hamilton · University of Southern California

Angela B. Mariotto · National Cancer Institute

Daniel Miller ·

Abstract

Clinically-tested patients with breast and ovarian cancer in two large, diverse states had 8% to 15% prevalence of actionable pathogenic variants. Substantial testing gaps and disparities among patients with ovarian cancer are targets for improvement.

Topics & Keywords

BRCA gene mutations in cancer DNA Repair Mechanisms Genomic variations and chromosomal abnormalities

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 37, Issue 15, pp. 1305-1315

DOI: 10.1200/jco.18.01854

Field-Weighted Citation Impact: 35.18