RETRACTED ARTICLE: Exosome-transmitted miR-128-3p increase chemosensitivity of oxaliplatin-resistant colorectal cancer

2019272 citationsJournal Articlegold Open Access

Authors

Tong Liu · Second Hospital of Shandong University

Xin Zhang · Qilu Hospital of Shandong University

Lutao Du · Second Hospital of Shandong University

Yunshan Wang · Second Hospital of Shandong University

Xiaoming Liu · Jining Traditional Chinese Medicine Hospital

Hui Tian · Qilu Hospital of Shandong University

Lili Wang

Abstract

Our results demonstrate that miR-128-3p delivery via exosomes represents a novel strategy enhancing chemosensitivity in CRC through negative regulation of Bmi1 and MRP5. Moreover, miR-128-3p may be a promising diagnostic and prognostic marker for oxaliplatin-based chemotherapy.

Topics & Keywords

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Molecular Cancer

Volume 18, Issue 1, pp. 43-43

DOI: 10.1186/s12943-019-0981-7

Field-Weighted Citation Impact: 16.65