Anticholinergic Drug Exposure and the Risk of Dementia

2019568 citationsJournal Articlehybrid Open Access

Authors

Carol Coupland · University of Nottingham

Trevor Hill · University of Nottingham

Tom Dening · Institute of Mental Health

Richard Morriss · Institute of Mental Health

Michael Moore · University of Southampton

Julia Hippisley–Cox · University of Oxford

Abstract

Exposure to several types of strong anticholinergic drugs is associated with an increased risk of dementia. These findings highlight the importance of reducing exposure to anticholinergic drugs in middle-aged and older people.

Topics & Keywords

Pharmaceutical Practices and Patient Outcomes Intensive Care Unit Cognitive Disorders Dementia and Cognitive Impairment Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA Internal Medicine

Volume 179, Issue 8, pp. 1084-1084

DOI: 10.1001/jamainternmed.2019.0677

Field-Weighted Citation Impact: 41.17