Dissociable effects of cannabis with and without cannabidiol on the human brain’s resting-state functional connectivity

201988 citationsJournal Article

Authors

Matthew B. Wall · Hammersmith Hospital

Rebecca Pope · University College London

Tom P. Freeman · University College London

Olivia S. Kowalczyk · Wellcome Centre for Human Neuroimaging

Lysia Demetriou · Hammersmith Hospital

Claire Mokrysz · University College London

Chandni Hindocha

Abstract

THC disrupts the DMN, and the PCC is a key brain region involved in the subjective experience of THC intoxication. CBD restores disruption of the salience network by THC, which may explain its potential to treat disorders of salience such as psychosis and addiction.

Topics & Keywords

Functional Brain Connectivity Studies Neuroscience and Neuropharmacology Research Cannabis and Cannabinoid Research

Publication Details

Published in: Journal of Psychopharmacology

Volume 33, Issue 7, pp. 822-830

DOI: 10.1177/0269881119841568

Field-Weighted Citation Impact: 7.55

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Dissociable effects of cannabis with and without cannabidiol on the human brain’s resting-state functional connectivity

Authors

Abstract

Topics & Keywords

Publication Details