Subgroups of monocytes predict cardiovascular events in patients with coronary heart disease. The PHAMOS trial (Prospective Halle Monocytes Study)

201933 citationsJournal Articlediamond Open Access

Authors

Florian Höpfner · Martin Luther University Halle-Wittenberg

Marrit Jacob · Leibniz Institute for Prevention Research and Epidemiology - BIPS

Christof Ulrich · Martin Luther University Halle-Wittenberg

Martin Ruß · Martin Luther University Halle-Wittenberg

Andreas Simm · Martin Luther University Halle-Wittenberg

Rolf Edgar Silber · Martin Luther University Halle-Wittenberg

Matthias Girndt

Abstract

The absolute counts of classical monocytes divided in tertiles are predictive of major adverse cardiac events in patients with CAD. A tremendous shift from classical to intermediate monocytes was also confirmed in patients with CAD. These data highlight the importance of CD14++ monocytes in cardiovascular diseases.

Topics & Keywords

Immune cells in cancer Inflammatory Biomarkers in Disease Prognosis Chemokine receptors and signaling

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Hellenic Journal of Cardiology

Volume 60, Issue 5, pp. 311-321

DOI: 10.1016/j.hjc.2019.04.012

Field-Weighted Citation Impact: 1.75