DsbA-L ameliorates high glucose induced tubular damage through maintaining MAM integrity

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Authors

Ming Yang · Second Xiangya Hospital of Central South University

Li Zhao · Central South University

Peng Gao · Central South University

Xuejing Zhu · Central South University

Yachun Han · Second Xiangya Hospital of Central South University

Xianghui Chen · Second Xiangya Hospital of Central South University

Li Li

Abstract

Our results indicate that DsbA-L exerts an antiapoptotic effect by maintaining MAM integrity, which is apparently disrupted in DN. FUND: This work was supported by the National Natural Science Foundation of China (81730018), the National Key R&D Program of China (2016YFC1305501) and NIH (DK60635).

Topics & Keywords

Mitochondrial Function and Pathology Autophagy in Disease and Therapy Endoplasmic Reticulum Stress and Disease

Publication Details

Published in: EBioMedicine

Volume 43, pp. 607-619

DOI: 10.1016/j.ebiom.2019.04.044

Field-Weighted Citation Impact: 3.08

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DsbA-L ameliorates high glucose induced tubular damage through maintaining MAM integrity

Authors

Abstract

Topics & Keywords

Publication Details