Ultrasensitive detection of cancer biomarkers by nickel-based isolation of polydisperse extracellular vesicles from blood

201957 citationsJournal Articlegold Open Access

Authors

Michela Notarangelo · University of Trento

Chiara Zucal · University of Trento

A. Modelska · University of Trento

Isabella Pesce · University of Trento

Giorgina Scarduelli · University of Trento

Cristina Potrich · Fondazione Bruno Kessler

Lorenzo Lunelli ·

Abstract

We propose NBI-combined approaches as simple, fast, and robust strategies to probe the tumor heterogeneity and contribute to the development of EV-based liquid biopsy studies. FUND: Associazione Italiana per la Ricerca sul Cancro (AIRC), Fondazione Cassa di Risparmio Trento e Rovereto (CARITRO), and the Italian Ministero Istruzione, Università e Ricerca (Miur).

Topics & Keywords

Extracellular vesicles in disease MicroRNA in disease regulation Cell Adhesion Molecules Research

UN Sustainable Development Goals

Reduced inequalitiesPeace, Justice and strong institutions

Publication Details

Published in: EBioMedicine

Volume 43, pp. 114-126

DOI: 10.1016/j.ebiom.2019.04.039

Field-Weighted Citation Impact: 2.65