Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression

2019584 citationsJournal Articlegold Open Access

Authors

Xiaoxu Huang · Jiangsu Province Hospital

Zheng Li · Jiangsu Province Hospital

Qiang Zhang · Jiangsu Province Hospital

Weizhi Wang · Jiangsu Province Hospital

Bowen Li · Jiangsu Province Hospital

Lu Wang · Jiangsu Province Hospital

Zhipeng Xu ·

Abstract

circAKT3 plays an important role in the resistance of GC to CDDP. Thus, our results highlight the potential of circAKT3 as a therapeutic target for GC patients receiving CDDP therapy.

Topics & Keywords

Circular RNAs in diseases MicroRNA in disease regulation Global Educational Reforms and Inequalities

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Molecular Cancer

Volume 18, Issue 1, pp. 71-71

DOI: 10.1186/s12943-019-0969-3

Field-Weighted Citation Impact: 38.72