Multidimensional dynamic experiments for data-rich process development of reactions in flow

201943 citationsJournal Article

Authors

Brian M. Wyvratt · Merck & Co., Inc., Rahway, NJ, USA (United States)

Jonathan P. McMullen · Merck Institute for Science Education

Shane T. Grosser · Merck Institute for Science Education

Abstract

The use of multidimensional dynamic flow experiments for reaction profiling and generation of an empirical surface response model for a Knoevenagel condensation reaction is described.

Topics & Keywords

Innovative Microfluidic and Catalytic Techniques Innovation Electrowetting and Microfluidic Technologies Microfluidic and Capillary Electrophoresis Applications

Publication Details

Published in: Reaction Chemistry & Engineering

Volume 4, Issue 9, pp. 1637-1645

DOI: 10.1039/c9re00078j

Field-Weighted Citation Impact: 2.28

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Multidimensional dynamic experiments for data-rich process development of reactions in flow

Authors

Abstract

Topics & Keywords

Publication Details