Early lesion detection with 18F-DCFPyL PET/CT in 248 patients with biochemically recurrent prostate cancer

201970 citationsJournal Articlehybrid Open Access

Authors

Maurits Wondergem · Noordwest Ziekenhuisgroep

B.H.E. Jansen · Amsterdam University Medical Centers

Friso M. van der Zant · Noordwest Ziekenhuisgroep

Tim M. van der Sluis · Amsterdam University Medical Centers

Remco J.J. Knol · Noordwest Ziekenhuisgroep

Ludwike W. M. van Kalmthout · University Medical Center Utrecht

Otto S. Hoekstra

Abstract

18F-DCFPyL PET/CT offers early detection of lesions in patients with BCR, even at PSA levels <0.5 ng/ml. These results appear to be comparable to those reported for 68Ga-PSMA and 18F-PSMA-1007, with potentially increased detection efficacy compared to 68Ga-PSMA for patients with PSA <2.0.

Topics & Keywords

Prostate Cancer Treatment and Research Prostate Cancer Diagnosis and Treatment Radiopharmaceutical Chemistry and Applications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: European Journal of Nuclear Medicine and Molecular Imaging

Volume 46, Issue 9, pp. 1911-1918

DOI: 10.1007/s00259-019-04385-6

Field-Weighted Citation Impact: 8.20