Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics

20183,222 citationsJournal Articlegold Open Access

Authors

Kelly Street · University of California, Berkeley

Davide Risso · Cornell University

Russell B. Fletcher · University of California, Berkeley

Diya Das · University of California, Berkeley

John Ngai · Innovative Genomics Institute

Nir Yosef · University of California, Berkeley

Elizabeth Purdom

Abstract

Slingshot is a uniquely robust and flexible tool which combines the highly stable techniques necessary for noisy single-cell data with the ability to identify multiple trajectories. Accurate lineage inference is a critical step in the identification of dynamic temporal gene expression.

Topics & Keywords

Single-cell and spatial transcriptomics Gene Regulatory Network Analysis Gene expression and cancer classification

Publication Details

Published in: BMC Genomics

Volume 19, Issue 1, pp. 477-477

DOI: 10.1186/s12864-018-4772-0

Field-Weighted Citation Impact: 67.05

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Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics

Authors

Abstract

Topics & Keywords

Publication Details