Methylome-wide association study provides evidence of particulate matter air pollution-associated DNA methylation

201988 citationsJournal Articlegold Open Access

Authors

Rahul Gondalia · University of North Carolina at Chapel Hill

Antoine Baldassari · University of North Carolina at Chapel Hill

Katelyn M. Holliday · University of North Carolina at Chapel Hill

Anne E. Justice · University of North Carolina at Chapel Hill

Raúl Méndez-Giráldez · University of North Carolina at Chapel Hill

James D. Stewart · University of North Carolina at Chapel Hill

Abstract

Ambient PM concentrations were associated with DNAm at genomic regions potentially related to poor health among racially, ethnically and environmentally diverse populations of U.S. women and men. Further investigation is warranted to uncover mechanisms through which PM-induced epigenomic changes may cause disease.

Topics & Keywords

Air Quality and Health Impacts Air Quality Monitoring and Forecasting Energy and Environment Impacts

UN Sustainable Development Goals

No povertyGood health and well-being

Publication Details

Published in: Environment International

Volume 132, pp. 104723-104723

DOI: 10.1016/j.envint.2019.03.071

Field-Weighted Citation Impact: 5.21