Cefepime neurotoxicity: thresholds and risk factors. A retrospective cohort study

2019136 citationsJournal Articlehybrid Open Access

Authors

L. Boschung-Pasquier · University Hospital of Bern

A. Atkinson · University Hospital of Bern

Lucas Kastner · University Hospital of Bern

Sarah Banholzer · University Hospital of Bern

Manuel Haschke · University Hospital of Bern

Niccolò Buetti · University Hospital of Bern

Dominique I. Furrer

Abstract

In individuals with risk factors for cefepime neurotoxicity, such as renal insufficiency, TDM should be systematically performed, aiming at trough concentrations <7.5 mg/L.

Topics & Keywords

Antibiotics Pharmacokinetics and Efficacy Antibiotic Resistance in Bacteria Urinary Tract Infections Management

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Microbiology and Infection

Volume 26, Issue 3, pp. 333-339

DOI: 10.1016/j.cmi.2019.06.028

Field-Weighted Citation Impact: 13.19