Low-density lipoprotein cholesterol and risk of intracerebral hemorrhage

2019191 citationsJournal Articlebronze Open Access

Authors

Chaoran Ma · Harvard University

M. Edip Gurol · Kailuan General Hospital

Zhe Huang · Kailuan General Hospital

Alice H. Lichtenstein · Kailuan General Hospital

Xiuyan Wang · Kailuan General Hospital

Yuzhen Wang · Massachusetts General Hospital

Samantha Neumann ·

Abstract

We observed a significant association between lower LDL-C and higher risk of ICH when LDL-C was <70 mg/dL, and the association became nonsignificant when LDL-C ≥70 mg/dL. These data can help determination of the ideal LDL range in patients who are at increased risk of both atherosclerotic disease and hemorrhagic stroke and guide planning of future lipid-lowering studies.

Topics & Keywords

Lipoproteins and Cardiovascular Health Aortic Thrombus and Embolism Antiplatelet Therapy and Cardiovascular Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neurology

Volume 93, Issue 5, pp. e445-e457

DOI: 10.1212/wnl.0000000000007853

Field-Weighted Citation Impact: 21.78