Association of Lifestyle and Genetic Risk With Incidence of Dementia

2019846 citationsJournal Articlehybrid Open Access

Authors

Ilianna Lourida · University of Exeter

Eilís Hannon · University of Exeter

Thomas J. Littlejohns · University of Oxford

Kenneth M. Langa · VA Center for Clinical Management Research

Elina Hyppönen · University of South Australia

Elżbieta Kuźma · University Medical Center Hamburg-Eppendorf

David J. Llewellyn

Abstract

Among older adults without cognitive impairment or dementia, both an unfavorable lifestyle and high genetic risk were significantly associated with higher dementia risk. A favorable lifestyle was associated with a lower dementia risk among participants with high genetic risk.

Topics & Keywords

Dementia and Cognitive Impairment Research Folate and B Vitamins Research Nutritional Studies and Diet

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA

Volume 322, Issue 5, pp. 430-430

DOI: 10.1001/jama.2019.9879

Field-Weighted Citation Impact: 52.93