Renal impairment is closely associated with plasma aldosterone concentration in patients with primary aldosteronism

201953 citationsJournal Articlebronze Open Access

Authors

Akiyuki Kawashima · Kyoto University

Masakatsu Sone · Kyoto University

Nobuya Inagaki · Kyoto University

Yoshiyu Takeda · Kanazawa University

Hiroshi Itoh · Keio University

Isao Kurihara · Keio University

Hironobu Umakoshi · Kyoto Medical Center

Abstract

Plasma aldosterone levels are closely associated with renal impairment in patients with PA. This is contrast to our earlier finding that the PAC was not itself linearly associated with cardiovascular events such as stroke or ischemic heart disease. The mechanism underlying the kidney damage in patients with PA may differ from that affecting the cardiovascular system.

Topics & Keywords

Hormonal Regulation and Hypertension Adrenal and Paraganglionic Tumors Blood Pressure and Hypertension Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: European Journal of Endocrinology

Volume 181, Issue 3, pp. 339-350

DOI: 10.1530/eje-19-0047

Field-Weighted Citation Impact: 3.51