Overeating Saturated Fat Promotes Fatty Liver and Ceramides Compared With Polyunsaturated Fat: A Randomized Trial

2019218 citationsJournal Articlehybrid Open Access

Authors

Fredrik Rosqvist · Uppsala University

Joel Kullberg · Uppsala University

Marcus Ståhlman · University of Gothenburg

Jonathan Cedernaes · Northwestern University

Kerstin Heurling · Uppsala University

Hans-Erik Johansson · Uppsala University

David Iggman ·

Abstract

SFA markedly induces liver fat and serum ceramides, whereas dietary PUFA prevents liver fat accumulation and reduces ceramides and hyperlipidemia during excess energy intake and weight gain in overweight individuals.

Topics & Keywords

Liver Disease Diagnosis and Treatment Fatty Acid Research and Health Diet and metabolism studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Clinical Endocrinology & Metabolism

Volume 104, Issue 12, pp. 6207-6219

DOI: 10.1210/jc.2019-00160

Field-Weighted Citation Impact: 15.19