Gushukang inhibits osteocyte apoptosis and enhances BMP-2/Smads signaling pathway in ovariectomized rats

201945 citationsJournal Articlehybrid Open Access

Authors

Shuang Chai · Guangzhou University of Chinese Medicine

Lei Wan · Guangzhou University of Chinese Medicine

Jili Wang · Guangzhou University of Chinese Medicine

Jiachun Huang · Guangzhou University of Chinese Medicine

Hongxing Huang · Guangzhou University of Chinese Medicine

Abstract

These data suggest that GSK exhibited protective effects on promoting bone formation and precluding osteocyte apoptosis. The underlying mechanism may be attributed to its regulation on BMP-2/Smads signaling pathway and Bcl2 family.

Topics & Keywords

Bone Metabolism and Diseases TGF-β signaling in diseases Reproductive System and Pregnancy

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Phytomedicine

Volume 64, pp. 153063-153063

DOI: 10.1016/j.phymed.2019.153063

Field-Weighted Citation Impact: 1.70