Characterization of binding, functional activity, and contractile responses of the selective 5‐HT<sub>1F</sub> receptor agonist lasmiditan

201971 citationsJournal Articlehybrid Open Access

Authors

Eloísa Rubio‐Beltrán · Erasmus MC

Alejandro Labastida‐Ramírez · Erasmus MC

Kristian Agmund Haanes · Erasmus MC

Antoon van den Bogaerdt · Erasmus University Rotterdam

Ad J.J.C. Bogers · Erasmus University Rotterdam

Eric Zanelli

Laurent Meeus · Euroscreen (Belgium)

Abstract

Lasmiditan is a selective 5-HT<sub>1F</sub> receptor agonist devoid of vasoconstrictor activity. This may represent a cardiovascular safety advantage when compared to the triptans.

Topics & Keywords

Migraine and Headache Studies Blood Pressure and Hypertension Studies Cardiovascular Syncope and Autonomic Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: British Journal of Pharmacology

Volume 176, Issue 24, pp. 4681-4695

DOI: 10.1111/bph.14832

Field-Weighted Citation Impact: 6.74