Early molecular oxidative stress biomarkers of ischemic penumbra in acute stroke

201951 citationsJournal Articlegreen Open Access

Authors

Svetlana Lorenzano · Tufts University

Natalia S. Rost · Tufts University

Muhib Khan · Tufts University

Hua Li · Tufts University

Leonardo M Batista · Tufts University

Aurauma Chutinet · Tufts University

R. Green · Tufts University

Abstract

Elevated hyperacute plasma levels of F2-isoP and ORAC are associated with radiographic evidence of mismatch and mismatch salvage in patients with AIS. If validated, these findings may add to our understanding of the role of oxidative stress in cerebral tissue fate during acute ischemia.

Topics & Keywords

Acute Ischemic Stroke Management Cerebrovascular and Carotid Artery Diseases Advanced MRI Techniques and Applications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neurology

Volume 93, Issue 13, pp. e1288-e1298

DOI: 10.1212/wnl.0000000000008158

Field-Weighted Citation Impact: 4.47