Gene-Based Risk Stratification for Cardiac Disorders in <i>LMNA</i> Mutation Carriers

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Authors

Suguru Nishiuchi

Takeru Makiyama

Takeshi Aiba

Kenzaburo Nakajima

Sayako Hirose · Hirose Electric (Japan)

Hirohiko Kohjitani

Yuta Yamamoto · Yamamoto Hospital

Abstract

The truncation mutations were associated with manifestation of cardiac phenotypes in <i>LMNA</i>-related cardiomyopathy, suggesting that genetic analysis might be useful for diagnosis and risk stratification.

Topics & Keywords

Nuclear Structure and Function RNA Research and Splicing Genomics and Chromatin Dynamics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation Cardiovascular Genetics

Volume 10, Issue 6

DOI: 10.1161/circgenetics.116.001603

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