<p>Aucubin Protects Chondrocytes Against IL-1β-Induced Apoptosis In Vitro And Inhibits Osteoarthritis In Mice Model</p>

2019206 citationsJournal Articlegold Open Access

Authors

Bowei Wang · Nanfang Hospital

Yiguo Jiang · Southern Medical University

Zilong Yao · Nanfang Hospital

Peisheng Chen · Xiamen University

Bin Yu · Nanfang Hospital

Shengnan Wang · Nanfang Hospital

Abstract

Our findings suggest that aucubin has a protective effect on articular cartilage and slowing progression of OA in a mouse model. This protective effect may result from inhibiting chondrocyte apoptosis and excessive ROS production.

Topics & Keywords

Osteoarthritis Treatment and Mechanisms Inflammatory mediators and NSAID effects Natural product bioactivities and synthesis

Publication Details

Published in: Drug Design Development and Therapy

Volume Volume 13, pp. 3529-3538

DOI: 10.2147/dddt.s210220

Field-Weighted Citation Impact: 13.01

Command Palette

&lt;p&gt;Aucubin Protects Chondrocytes Against IL-1β-Induced Apoptosis In Vitro And Inhibits Osteoarthritis In Mice Model&lt;/p&gt;

Authors

Abstract

Topics & Keywords

Publication Details

<p>Aucubin Protects Chondrocytes Against IL-1β-Induced Apoptosis In Vitro And Inhibits Osteoarthritis In Mice Model</p>