20-Year Follow-up of Statins in Children with Familial Hypercholesterolemia

2019619 citationsJournal Articlebronze Open Access

Authors

Ilse K. Luirink · Center for Vascular Biology Research

Albert Wiegman

D. Meeike Kusters

Michel H. Hof

Jaap W. Groothoff

Eric de Groot · Amsterdam University Medical Centers

John J.P. Kastelein

Barbara A. Hutten

Abstract

In this study, initiation of statin therapy during childhood in patients with familial hypercholesterolemia slowed the progression of carotid intima-media thickness and reduced the risk of cardiovascular disease in adulthood. (Funded by the AMC Foundation.).

Topics & Keywords

Lipoproteins and Cardiovascular Health

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 381, Issue 16, pp. 1547-1556

DOI: 10.1056/nejmoa1816454

Field-Weighted Citation Impact: 64.14