First‐trimester pre‐eclampsia biomarker profiles in Asian population: multicenter cohort study

201945 citationsJournal Article

Authors

Piya Chaemsaithong · Chinese University of Hong Kong

Daljit Singh Sahota · Chinese University of Hong Kong

Ritsuko K. Pooh

Mingming Zheng · Nanjing Drum Tower Hospital

Richard Ma · First Affiliated Hospital of Kunming Medical University

Noppadol Chaiyasit · King Chulalongkorn Memorial Hospital

Kaoru Koide · Showa University Hospital

Abstract

Owing to the anthropometric differences in Asian compared with Caucasian women, significant differences in biomarker MoM values for PE screening, particularly MAP and PlGF MoMs, were noted in Asian populations compared with the expected values based on European-derived formulae. If reliable and consistent patient-specific risks for preterm PE are to be reported, adjustment for additional factors or development of Asian-specific formulae for the calculation of biomarker MoMs is required. We have also demonstrated the importance and need for regular quality assessment of biomarker values. Copyright © 2019 ISUOG. Published by John Wiley & Sons Ltd.

Topics & Keywords

Pregnancy and preeclampsia studies Preterm Birth and Chorioamnionitis Birth, Development, and Health

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Ultrasound in Obstetrics and Gynecology

Volume 56, Issue 2, pp. 206-214

DOI: 10.1002/uog.21905

Field-Weighted Citation Impact: 4.59