Association of Baclofen With Encephalopathy in Patients With Chronic Kidney Disease

201975 citationsJournal Articlebronze Open Access

Authors

Flory T. Muanda · Western University

Matthew A. Weir · Western University

Lavanya Bathini · Institute for Clinical Evaluative Sciences

Peter G. Blake · Western University

Kianna Chauvin · Western University

Stephanie N. Dixon · Institute for Clinical Evaluative Sciences

Eric McArthur

Abstract

Among older patients with CKD who were newly prescribed baclofen, the 30-day incidence of encephalopathy was increased among those prescribed higher doses compared with lower doses. If verified, these risks should be balanced against the benefits of baclofen use.

Topics & Keywords

Neurological and metabolic disorders Parkinson's Disease Mechanisms and Treatments Botulinum Toxin and Related Neurological Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA

Volume 322, Issue 20, pp. 1987-1987

DOI: 10.1001/jama.2019.17725

Field-Weighted Citation Impact: 3.37