Effect of Metabolic Traits on the Risk of Cirrhosis and Hepatocellular Cancer in Nonalcoholic Fatty Liver Disease

2019307 citationsJournal Article

Authors

Fasiha Kanwal · Michael E. DeBakey VA Medical Center

Jennifer R. Kramer · Michael E. DeBakey VA Medical Center

Liang Li · The University of Texas MD Anderson Cancer Center

Jianliang Dai · The University of Texas MD Anderson Cancer Center

Yamini Natarajan · Michael E. DeBakey VA Medical Center

Xian Yu · Michael E. DeBakey VA Medical Center

Steven M. Asch

Abstract

Each additional metabolic trait increased the risk of cirrhosis and HCC in patients with NAFLD. Diabetes conferred the highest risk of progression to HCC. Patients with diabetes and coexisting hypertension and obesity may be important targets for secondary prevention.

Topics & Keywords

Liver Disease Diagnosis and Treatment Diet, Metabolism, and Disease Liver Disease and Transplantation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Hepatology

Volume 71, Issue 3, pp. 808-819

DOI: 10.1002/hep.31014

Field-Weighted Citation Impact: 20.12