A neurobiological mechanism linking transportation noise to cardiovascular disease in humans

2019152 citationsJournal Articlegreen Open Access

Authors

Michael T. Osborne · Massachusetts General Hospital

Azar Radfar · Harvard University

Malek Hassan · Massachusetts General Hospital

Shady Abohashem · Harvard University

Blake Oberfeld · Massachusetts General Hospital

Tomas Patrich · Massachusetts General Hospital

Brian Tung ·

Abstract

Our findings suggest that noise exposure associates with MACE via a mechanism that begins with increased stress-associated limbic (amygdalar) activity and includes heightened arterial inflammation. This potential neurobiological mechanism linking noise to CVD merits further evaluation in a prospective population.

Topics & Keywords

Noise Effects and Management Hearing Loss and Rehabilitation Hearing, Cochlea, Tinnitus, Genetics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: European Heart Journal

Volume 41, Issue 6, pp. 772-782

DOI: 10.1093/eurheartj/ehz820

Field-Weighted Citation Impact: 24.72