Deferoxamine and Curcumin Loaded Nanocarriers Protect Against Rotenone-Induced Neurotoxicity

201946 citationsJournal Articlegreen Open Access

Authors

Leah Mursaleen · University of Westminster

Satyanarayana Somavarapu · The London College

Mohammed Gulrez Zariwala · University of Westminster

Abstract

This study demonstrates for the first time the formulation and delivery using P68 and P68+DQA curcumin and/or DFO nanocarriers to protect against oxidative stress induced by a rotenone PD model. This strategy to combine antioxidants with iron chelators may provide a novel approach to fully utilise their therapeutic benefit for PD.

Topics & Keywords

Curcumin's Biomedical Applications Conducting polymers and applications Nanoparticle-Based Drug Delivery

Publication Details

Published in: Journal of Parkinson s Disease

Volume 10, Issue 1, pp. 99-111

DOI: 10.3233/jpd-191754

Field-Weighted Citation Impact: 2.01

Command Palette

Deferoxamine and Curcumin Loaded Nanocarriers Protect Against Rotenone-Induced Neurotoxicity

Authors

Abstract

Topics & Keywords

Publication Details