Exposure to multiple metals in early pregnancy and gestational diabetes mellitus: A prospective cohort study

2019151 citationsJournal Articlegold Open Access

Authors

Xiaoyi Wang · Huazhong University of Science and Technology

Duan Gao · Huazhong University of Science and Technology

Guofu Zhang · Xinxiang Medical University

Xu Zhang · Huazhong University of Science and Technology

Qian Li · Huazhong University of Science and Technology

Qin Gao · Huazhong University of Science and Technology

Renjuan Chen

Abstract

To the best of our knowledge, this study is the first to demonstrate that increased concentrations of urinary Ni in early pregnancy are associated with an elevated risk of GDM, either evaluated individually or as a metal mixture. All six metals mixed exposure was positively associated with the risk of GDM, while Sb and Ni were demonstrated more important effects than the other four metals in the mixture.

Topics & Keywords

Heavy Metal Exposure and Toxicity Trace Elements in Health Mercury impact and mitigation studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Environment International

Volume 135, pp. 105370-105370

DOI: 10.1016/j.envint.2019.105370

Field-Weighted Citation Impact: 7.48