Telomere length associations with cognition depend on Alzheimer's disease biomarkers

201948 citationsJournal Articlegold Open Access

Authors

Emily R. Mahoney · Vanderbilt University Medical Center

Logan Dumitrescu · Vanderbilt University Medical Center

Mabel Seto · Vanderbilt University Medical Center

Kelly Nudelman · Indiana University School of Medicine

Rachel F. Buckley · Massachusetts General Hospital

Katie A. Gifford · Vanderbilt University Medical Center

Andrew J. Saykin

Abstract

Telomere associations with cognition shift with AD progression, with longer telomeres related to worse outcomes as pathology increases, highlighting the need for further investigation of telomere length along the AD neuropathological cascade.

Topics & Keywords

Telomeres, Telomerase, and Senescence Genetics, Aging, and Longevity in Model Organisms

Publication Details

Published in: Alzheimer s & Dementia Translational Research & Clinical Interventions

Volume 5, Issue 1, pp. 883-890

DOI: 10.1016/j.trci.2019.11.003

Field-Weighted Citation Impact: 2.35

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Telomere length associations with cognition depend on Alzheimer's disease biomarkers

Authors

Abstract

Topics & Keywords

Publication Details