Genomic and Phenotypic Characterization of a Broad Panel of Patient-Derived Xenografts Reflects the Diversity of Glioblastoma

2019229 citationsJournal Articlebronze Open Access

Authors

Rachael A. Vaubel · Mayo Clinic

Shulan Tian · Mayo Clinic

Dioval Remonde · East Carolina University

Mark A. Schroeder · Mayo Clinic

Ann C. Mladek · Mayo Clinic

Gaspar J. Kitange · Mayo Clinic

Alissa Caron · Mayo Clinic

Abstract

Our PDX panel captures the molecular heterogeneity of glioblastoma and recapitulates many salient genetic and phenotypic features. All models and genomic data are openly available to investigators.

Topics & Keywords

Glioma Diagnosis and Treatment Cancer Genomics and Diagnostics 3D Printing in Biomedical Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 26, Issue 5, pp. 1094-1104

DOI: 10.1158/1078-0432.ccr-19-0909

Field-Weighted Citation Impact: 11.55