KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3

2019585 citationsJournal Articlegold Open Access

Authors

Tian Lan · Sichuan University

Hui Li · State Key Laboratory of Biotherapy

Zhang Delin · Guizhou Provincial People's Hospital

Lin Xu · State Key Laboratory of Biotherapy

Hailing Liu · State Key Laboratory of Biotherapy

Xiangyong Hao · State Key Laboratory of Biotherapy

Xiaokai Yan

Abstract

Our study proposed a complex KIAA1429-GATA3 regulatory model based on m6A modification and provided insights into the epi-transcriptomic dysregulation in hepatocarcinogenesis and metastasis.

Topics & Keywords

RNA modifications and cancer Cancer-related molecular mechanisms research Cancer-related gene regulation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Molecular Cancer

Volume 18, Issue 1, pp. 186-186

DOI: 10.1186/s12943-019-1106-z

Field-Weighted Citation Impact: 33.66