The influence of time to adrenaline administration in the Paramedic 2 randomised controlled trial

202078 citationsJournal Articlehybrid Open Access

Authors

Gavin D. Perkins · University of Warwick

Claire Kenna · University of Warwick

Chen Ji · University of Warwick

Charles D. Deakin · South Western Ambulance Service NHS Foundation Trust

Jerry P. Nolan · Royal United Hospital

Tom Quinn · St George's, University of London

Charlotte Scomparin

Abstract

The rate of return of spontaneous circulation, survival and favourable neurological outcomes decrease over time. As time to drug treatment increases, adrenaline increases the chances of return of spontaneous circulation. Longer term outcomes were not affected by the time to adrenaline administration. (ISRCTN73485024).

Topics & Keywords

Cardiac Arrest and Resuscitation Traumatic Brain Injury Research Intensive Care Unit Cognitive Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Intensive Care Medicine

Volume 46, Issue 3, pp. 426-436

DOI: 10.1007/s00134-019-05836-2

Field-Weighted Citation Impact: 9.80