Menadione reduces <i>CDC25B</i> expression and promotes tumor shrinkage in gastric cancer

202014 citationsJournal Articlegold Open Access

Authors

Amanda Braga Bona · Universidade Federal do Pará

Danielle Queiroz Calcagno · Universidade Federal do Pará

Helem Ferreira Ribeiro

José Augusto Pereira Carneiro Muniz · Ministério da Saúde

Giovanny R. Pinto · Universidade Federal do Piauí

Carlos Alberto Machado da Rocha · Federal Ministry of Science & Technology

Antônio Carlos Cunha Lacreta · Universidade Federal de Lavras

Abstract

We suggest this compound may be an important ally of chemotherapeutics in the treatment of gastric cancer. In addition, CDC25B has proven to be an effective target for investigation and development of new therapeutic strategies for this malignancy.

Topics & Keywords

RNA modifications and cancer MicroRNA in disease regulation Epigenetics and DNA Methylation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Therapeutic Advances in Gastroenterology

Volume 13, pp. 1756284819895435-1756284819895435

DOI: 10.1177/1756284819895435

Field-Weighted Citation Impact: 0.66