Gait variability as digital biomarker of disease severity in Huntington’s disease

202056 citationsJournal Articlehybrid Open Access

Authors

Heiko Gaßner · Universitätsklinikum Erlangen

Dennis Jensen · Universitätsklinikum Erlangen

Franz Marxreiter · Friedrich-Alexander-Universität Erlangen-Nürnberg

Anja Kletsch · George Huntington Institute

Stefan Bohlen · George Huntington Institute

Robin Schubert · George Huntington Institute

Lisa M. Muratori

Abstract

Sensor-based gait variability parameters were identified as clinically most relevant digital biomarker for gait impairment in HD. Altered gait variability represents characteristic irregularity of gait in HD and reflects disease severity.

Topics & Keywords

Genetic Neurodegenerative Diseases Neurological disorders and treatments Botulinum Toxin and Related Neurological Disorders

Publication Details

Published in: Journal of Neurology

Volume 267, Issue 6, pp. 1594-1601

DOI: 10.1007/s00415-020-09725-3

Field-Weighted Citation Impact: 3.53

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Gait variability as digital biomarker of disease severity in Huntington’s disease

Authors

Abstract

Topics & Keywords

Publication Details