Assessing accuracy of Weibull shape parameter estimate from historical studies for subsequent sample size calculation in clinical trials with time-to-event outcome

202015 citationsJournal Articlegold Open Access

Authors

Milind A. Phadnis · University of Kansas Medical Center

Palash Sharma · University of Kansas Medical Center

Nadeesha Thewarapperuma · University of Kansas Medical Center

Prabhakar Chalise · University of Kansas Medical Center

Abstract

We conclude that assessing the accuracy of Weibull shape parameter estimate is important before it can be used to conduct sample size calculations for a subsequent trial.

Topics & Keywords

Statistical Methods in Clinical Trials Statistical Methods and Inference Statistical Methods and Bayesian Inference

UN Sustainable Development Goals

Peace, Justice and strong institutions

Publication Details

Published in: Contemporary Clinical Trials Communications

Volume 17, pp. 100548-100548

DOI: 10.1016/j.conctc.2020.100548

Field-Weighted Citation Impact: 1.54