Persistence and clearance of viral RNA in 2019 novel coronavirus disease rehabilitation patients

2020858 citationsJournal Articlegold Open Access

Authors

Yun Ling · Shanghai Public Health Clinical Center

Shui-Bao Xu · Shanghai Public Health Clinical Center

Yi-Xiao Lin · Shanghai Public Health Clinical Center

Di Tian · Shanghai Public Health Clinical Center

Zhao-Qin Zhu · Shanghai Public Health Clinical Center

Fa-Hui Dai · Shanghai Public Health Clinical Center

Fan Wu

Abstract

In brief, as the clearance of viral RNA in patients' stools was delayed compared to that in oropharyngeal swabs, it is important to identify viral RNA in feces during convalescence. Because of the delayed clearance of viral RNA in the glucocorticoid treatment group, glucocorticoids are not recommended in the treatment of COVID-19, especially for mild disease. The duration of RNA detection may relate to host cell immunity.

Topics & Keywords

COVID-19 Clinical Research Studies SARS-CoV-2 and COVID-19 Research SARS-CoV-2 detection and testing

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Chinese Medical Journal

Volume 133, Issue 9, pp. 1039-1043

DOI: 10.1097/cm9.0000000000000774

Field-Weighted Citation Impact: 21.14