<i>Helicobacter pylori</i>first‐line and rescue treatments in patients allergic to penicillin: Experience from the European Registry on<i>H pylori</i>management (Hp‐EuReg)

In patients allergic to penicillin, a triple combination with PPI + C + M should not be generally recommended as a first-line treatment, while a quadruple regimen with PPI + B + T + M seems to be a better option. As a rescue treatment, this quadruple regimen (if not previously prescribed) or a triple regimen with PPI + C + L could be used but achieved suboptimal (<80%) results.