Mesenchymal stem cells ameliorate myocardial fibrosis in diabetic cardiomyopathy via the secretion of prostaglandin E2

2020111 citationsJournal Articlegold Open Access

Authors

Liyuan Jin · Chinese People's Liberation Army

Jinying Zhang · Chinese People's Liberation Army

Zihui Deng · Chinese People's Liberation Army

Jiejie Liu · Chinese PLA General Hospital

Weidong Han · Chinese PLA General Hospital

Guang‐Hui Chen · Chinese PLA General Hospital

Yiling Si

Abstract

Our results indicated that MSC infusion could ameliorate cardiac fibrosis and dysfunction in DCM rats. The underlying mechanisms might involve the function of PGE2 secreted by MSCs.

Topics & Keywords

Mesenchymal stem cell research Tissue Engineering and Regenerative Medicine Electrospun Nanofibers in Biomedical Applications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Stem Cell Research & Therapy

Volume 11, Issue 1, pp. 122-122

DOI: 10.1186/s13287-020-01633-7

Field-Weighted Citation Impact: 7.33