Delivery of genome editing tools: A promising strategy for HPV-related cervical malignancy therapy

202033 citationsReview

Authors

Shahin Aghamiri · Shahid Beheshti University of Medical Sciences

Sam Talaei · Shahid Beheshti University of Medical Sciences

Soheil Roshanzamiri · Shahid Beheshti University of Medical Sciences

Farshid Zandsalimi · Tehran University of Medical Sciences

Elnaz Fazeli · Shahid Beheshti University of Medical Sciences

Mansur Aliyu · Tehran University of Medical Sciences

Omid Kheiry Avarvand

Abstract

The combination of nanoparticle-based delivery systems and genome-editing tools is a promising powerful strategy for cervical cancer therapy. The most significant limitations of this strategy that need to be focused on are low efficiency and off-target events.

Topics & Keywords

CRISPR and Genetic Engineering Virus-based gene therapy research Viral Infectious Diseases and Gene Expression in Insects

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Expert Opinion on Drug Delivery

Volume 17, Issue 6, pp. 753-766

DOI: 10.1080/17425247.2020.1747429

Field-Weighted Citation Impact: 1.57

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