Different Mismatch Concepts for Magnetic Resonance Imaging–Guided Thrombolysis in Unknown Onset Stroke

202028 citationsJournal Articlebronze Open Access

Authors

Lauranne Scheldeman · Vlaams Instituut voor Biotechnologie

Anke Wouters · Vlaams Instituut voor Biotechnologie

Florent Boutitie · Université Claude Bernard Lyon 1

Patrick Dupont · KU Leuven

Søren Christensen · NordGen

Bastian Cheng · Universität Hamburg

Martin Ebinger ·

Abstract

Evaluating both the DWI-FLAIR and PWI-DWI mismatch patterns in patients with unknown time of stroke onset will result in the highest yield of thrombolysis treatment. The treatment benefit of alteplase in patients with a DWI-FLAIR mismatch seems to be driven not merely by the presence of a PWI-DWI mismatch, although this analysis was underpowered. ANN NEUROL 2020;87:931-938.

Topics & Keywords

Acute Ischemic Stroke Management Cerebrovascular and Carotid Artery Diseases Venous Thromboembolism Diagnosis and Management

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Annals of Neurology

Volume 87, Issue 6, pp. 931-938

DOI: 10.1002/ana.25730

Field-Weighted Citation Impact: 3.64