CPI-613 rewires lipid metabolism to enhance pancreatic cancer apoptosis via the AMPK-ACC signaling

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Authors

Lixia Gao · Chongqing University of Arts and Sciences

Zhigang Xu · Chongqing University of Arts and Sciences

Zheng Huang · Chongqing University of Arts and Sciences

Yan Tang · Chongqing University of Arts and Sciences

Donglin Yang · Chongqing University of Arts and Sciences

Jiuhong Huang · Chongqing University of Arts and Sciences

Leilei He

Abstract

These findings explore the critical role of lipid metabolism in apoptosis, providing new insights into the AMPK-ACC signaling axis in crosstalk between lipid metabolism and apoptosis in CPI-613 treatment.

Topics & Keywords

Cancer, Hypoxia, and Metabolism Cancer, Lipids, and Metabolism Biochemical Acid Research Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Experimental & Clinical Cancer Research

Volume 39, Issue 1, pp. 73-73

DOI: 10.1186/s13046-020-01579-x

Field-Weighted Citation Impact: 5.43